Human immunoglobulin ameliorates rat experimental autoimmune neuritis
نویسندگان
چکیده
منابع مشابه
Human immunoglobulin ameliorates rat experimental autoimmune neuritis.
Human immunoglobulin is an effective treatment for Guillain-Barré syndrome, although the mechanism of action is not understood. We have investigated the effect of human immunoglobulin in an animal model of Guillain-Barré syndrome, namely experimental autoimmune neuritis (EAN), induced in Lewis rats by immunization with bovine spinal root myelin. Human immunoglobulin administered intraperitoneal...
متن کاملAnti-inflammatory and immunomodulatory potential of human immunoglobulin applied intrathecally in Lewis rat experimental autoimmune neuritis
Intravenous human immunoglobulins dominate in the treatment of autoimmune neuropathies. We introduce intrathecal application as a new option for experimental autoimmune neuritis in Lewis rats. After immunisation with neuritogenic P2 peptide, we show a therapeutic and preventive effect of intrathecal human immunoglobulins (5-40mg/kg) on clinical and electrophysiological neuritis signs. Histology...
متن کاملCorrection: Dimethyl Fumarate Ameliorates Lewis Rat Experimental Autoimmune Neuritis and Mediates Axonal Protection
Fig 2 and Fig 4 are swapped. The image in Fig 2 should be the image in Fig 4 and the image in Fig 4 should be the image in Fig 2. The captions remain unchanged. The publisher apologizes for the error. Please see the corrected Fig 2 and Fig 4 here. open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reprod...
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Erythropoietin (EPO) is a pleiotropic cytokine originally identified for its role in erythropoiesis. In addition, in various preclinical models EPO exhibited protective activity against tissue injury. There is an urgent need for potent treatments of autoimmune driven disorders of the peripheral nervous system (PNS), such as the Guillain-Barré syndrome (GBS), a disabling autoimmune disease assoc...
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ژورنال
عنوان ژورنال: Brain
سال: 1997
ISSN: 1460-2156
DOI: 10.1093/brain/120.9.1533